Here's a comparison: Semaglutide is readily accessible in California through healthcare providers and compounding pharmacies
Down 58 pounds and actually living my life again instead of just surviving each day
(2023) found that GLP-1 receptor agonists reduced the risk of lower limb amputation by 43% compared to sulfonylureas (HR: 0.57, 95% CI: 0.390.84), with the greatest risk reduction observed in long-term users (HR: 0.44, 95% CI: 0.270.72).(26) However, GLP-1 receptor agonists did not significantly impact diabetic foot ulcer incidence (HR: 1.08, 95% CI: 0.871.35)
Its also before factoring in people who may seek these drugs for aesthetic purposes, a kind of Botox of the body
Weekly injections are manageable for most patients, but adherence over years of treatment is a real challenge
Discuss appropriate monitoring with your clinician if using for longevity-focused goals